Uncovering the role of FOXO1 in vascular development and transcriptional dynamics in endothelial cells

FOXO1, a key transcription factor in cellular processes, governs metabolism, apoptosis, and aging. Despite its significance, the comprehensive regulation of FOXO1 in endothelial cells (EC) remains unexplored.

Phys.org
Exquisite control of #LPS-induced #inflammatory signaling: #TDAG51 expressed downstream of Toll-like receptor #TLR stimulation interacts with #FoxO1 and enhances its activity in production of inflammatory mediators
https://www.embopress.org/doi/10.15252/embj.2022111867