#FlyBase release FB2025_04 is live. There's a couple of major changes in this release. First, we've added many new bulk files to the Downloads page. https://flybase.org/downloads/bulkdata (you can find descriptions of the contents and format of each file here https://wiki.flybase.org/wiki/FlyBase:Downloads_Overview)

New bulk downloads include:
• Aberrations - gene deletion/duplication data
• Split system combinations
• Human disease model reports
• Single Cell RNA-Seq Metadata
• Gene model status and annotation comments
(there's more!)

There's an update on the state of FlyBase on the FlyBase.org front page.

You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase.

We express enormous gratitude to the people, labs, groups, and foundations who have already helped us. #FlyBase #Drosophila

Plea from the #ISMBECCB2025 keynote Q&A that we all cite the databases and resources (and software!) that is used.

For example, #Flybase had just over 100 citations in 2024 - yet used far more than this which undermines demonstrating impact with funders.

Whoever is running crawlers on FlyBase – likely for nefarious "AI" purposes – may you please stop abusing this service: you are killing it. I know that, of course, you won't: anything not nailed to the ground you consider yours for the taking. These attitudes can only foster walled gardens – login requirements, at least – or entirely going dark, drawing this resource away from the general public. Everyone loses, including you. If you wanted the whole of FlyBase, an email or a site visit would have resulted in a hard drive full of data – it's public after all.

"FlyBase’s servers have been experiencing an unprecedented amount of traffic recently, which has been causing the site to crash. We have been working on how to implement a system for banning IPs in a way that allows the site to stay online as much as possible, while affecting the fewest number of legitimate users. Without these IP-blocking measures, FlyBase would be down most of the time."

#FlyBase @FlyBase