In situ structure of a bacterial flagellar motor at subnanometre resolution reveals adaptations for increased torque | Nature Microbiology

https://www.nature.com/articles/s41564-025-02012-9

#CryoEM #evolution #bacteria #flagella #motor

In situ structure of a bacterial flagellar motor at subnanometre resolution reveals adaptations for increased torque - Nature Microbiology

In situ cryoEM and modelling of the Campylobacter jejuni flagellar motor characterize the periplasmic scaffold and the structural basis for increased torque generation.

Nature

This reminds me...in grad school (~2013), I came across research about bacteria locomotion, and the bacteria have multiple flagella that form a bundle that twists together.

That was so confusing to me. I imagined them all twisted together, and then each flagellum trying to twist from its own motor. It seems like there would be a jam.

Now I came across two papers that help make sense of it. In both papers they created a scale model of how bacteria flagellum bundle. It seems that the multiple flagella rotate next to each other but do not actually tangle https://www.bu.edu/fluidlab/files/2016/01/particle-image-velocimetry.pdf The second paper helped me to see it better. The helixes of the flagella line up and are in phase, so they effectively get out of each others way as they rotate. In the scale models it did jam if they were driven to hard, which meshed with my intuition. https://www.pnas.org/doi/full/10.1073/pnas.2633596100

#flagella

Bacteria-inspired robot uses 12 spinning flagella to roam underwater

An underwater drone with long, spinning arms like the flagella of bacteria could survey the seas without endangering marine life, its creators claim

New Scientist
This has me amazed. Bacteria and sperm propel themselves around with flagella. These #flagella have literal electric motors. We now know the structure of these amazing tiny machines. The #evolution of these is even more amazing than the evolution of eyes, imo. https://www.youtube.com/watch?v=VPSm9gJkPxU
Nature's Incredible ROTATING MOTOR (It’s Electric!) - Smarter Every Day 300

YouTube

Follow the leader: A new study of #flagella in #algae reveals how they coordinate their movements to ensure cells steer efficiently https://elifesciences.org/digests/86102/follow-the-leader #protists #microbes

The younger flagellum sets the beat for #Chlamydomonas reinhardtii https://elifesciences.org/articles/86102

"To steer, C. reinhardtii adjusts the strength of the strokes made by each flagellum. Despite this asymmetry, the flagella must continue to beat in synchrony to move efficiently."

Follow the leader

A new study of flagella in algae reveals how they coordinate their movements to ensure cells steer efficiently.

eLife Sciences Publications, Ltd

Widal Test in Serology: Understanding its Significance and Limitations

#CellWallAntigen, #Flagella, #FlagellarAntigens, #HAntigen, #OAntigen, #Salmonella, #SalmonellaInfection, #SalmonellaTreatment, #SalmonellaTyphi, #Serology, #Typhoid, #TyphoidFever, #WidalTest #Immunology The Widal test, developed by Georges-Fernand Widal in 1896, is a serological test used to diagnose typhoid fever caused by…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More…

https://micrordt.wordpress.com/2024/05/15/widal-test-in-serology-understanding-its-significance-and-limitations/

Widal Test in Serology: Understanding its Significance and Limitations

#CellWallAntigen, #Flagella, #FlagellarAntigens, #HAntigen, #OAntigen, #Salmonella, #SalmonellaInfection, #SalmonellaTreatment, #SalmonellaTyphi, #Serology, #Typhoid, #TyphoidFever, #WidalTest #Imm…

Medical Microbiology & RDT Labs

Flagellum, shift into reverse gear! https://schaechter.asmblog.org/schaechter/2024/05/hey-flagellum-shift-into-reverse-gear.html

Structural basis of directional switching by the bacterial flagellum https://pubmed.ncbi.nlm.nih.gov/38459206/

"In a manual gearbox, a gearwheel is inserted between the countershaft and the drive shaft. This reverses the rotation. #Flagella of E. coli, Salmonella #bacteria have found a smart solution to do without an additional wheel: they run their engine along the outside of a gearwheel or, if they reverse the direction of rotation, on its inside"

The Gray Staining Method: Unveiling the Microbial Mysteries of Flagella

#Bacteria, #BacteriaIdentification, #Flagella, #FlagellaStaining #Bacteriology Introduction Flagella, the whip-like appendages protruding from the surface of many microorganisms, are essential for various biological functions such as…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/05/10/the-gray-staining-method-unveiling-the-microbial-mysteries-of-flagella/

The Gray Staining Method: Unveiling the Microbial Mysteries of Flagella

#Bacteria, #BacteriaIdentification, #Flagella, #FlagellaStaining #Bacteriology Introduction Flagella, the whip-like appendages protruding from the surface of many microorganisms, are essential for …

Medical Microbiology & RDT Labs

Unveiling the Microbial World: The Gray Staining Method of Flagella

#Flagella, #FlagellaStaining, #GrayStaining, #Microbiology #Microbiology In the intricate realm of microbiology, where organisms too small for the naked eye wield immense significance, unraveling their mysteries…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/05/06/unveiling-the-microbial-world-the-gray-staining-method-of-flagella/

Unveiling the Microbial World: The Gray Staining Method of Flagella

#Flagella, #FlagellaStaining, #GrayStaining, #Microbiology #Microbiology In the intricate realm of microbiology, where organisms too small for the naked eye wield immense significance, unraveling t…

Medical Microbiology & RDT Labs

Flagella and Motility

#BasalBody, #Flagella, #FlagellaFilament, #FlagellaHook, #FlagellaMovement, #UltraStructureOfFlagella #Microbiology Most motile procaryotes move by use of flagella (s. flagellum). Flagella is a threadlike locomotor appendages extending outward from the…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/05/03/flagella-and-motility/

Flagella and Motility

#BasalBody, #Flagella, #FlagellaFilament, #FlagellaHook, #FlagellaMovement, #UltraStructureOfFlagella #Microbiology Most motile procaryotes move by use of flagella (s. flagellum). Flagella is a thr…

Medical Microbiology & RDT Labs