A research team at the University of Münster has investigated for the first time how the confrontation of bacteria with hosts that have an activated innate immune system affects the evolution of bacterial virulence. #ExperimentalEvolution

Innate immune memory influence...
Innate immune memory influences the evolution of pathogens

The news portal offers current information about studies, research and life at Münster University.

Two stages of evolution... @grantkinsler @gsherloc @petrovadmitri use #ExperimentalEvolution in yeast to show that while 1st-step mutants appear pleiotropic in nature, 2nd-step mutations show a shift towards modular adaptation #PLOSBiology https://plos.io/4glXoXJ
A high-resolution two-step evolution experiment in yeast reveals a shift from pleiotropic to modular adaptation

Evolution is expected to involve mutations that are small and modular in effect, but recent findings suggest that mutations early in an adaptive process can have strong and pleiotropic effects. This study uses experimental evolution in yeast to show that while first-step mutants appear pleiotropic in nature, second-step mutations show a shift towards modular adaptation.

Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community
#MicrobialEcology #EvolutionaryBiology #ExperimentalEvolution #science

https://www.nature.com/articles/s41467-024-51702-1#ref-CR13

Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community - Nature Communications

Here, the authors investigate the mechanisms behind mutualism with an engineered microbial community, finding that repeated indirect selection for enhanced metabolic dependencies may be a common factor in the evolution of mutualistic communities.

Nature

Our colleagues of the #EvolutionaryBiology group at #ETHZurich have just published https://www.myxoee.org/, a website on #myxobacteria #ExperimentalEvolution. Anyone interested in the evolution of sociality, cooperation and predation should have a look!

#myxococcus #microbiology #bacteria #evolution

MyxoEE

Evolution experiments with myxobacteria – MyxoEEs – have been used to address many evolutionary questions and are summarised at myxoee.org

MyxoEE

Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community
#evolution #ecology #ExperimentalEvolution

https://www.biorxiv.org/content/10.1101/2024.03.30.587424v1

Tuning of protein folding systems can open a path to the evolution of multicellularity.
#evolution #EvolutionaryBiology #multicellularity #proteome #ExperimentalEvolution #MuLTEE

https://www.science.org/doi/10.1126/sciadv.adn2706

The collapse of cooperation during range expansion of Pseudomonas aeruginosa
#evolution #EvolutionaryBiology #ExperimentalEvolution

https://www.nature.com/articles/s41564-024-01627-8

The collapse of cooperation during range expansion of Pseudomonas aeruginosa - Nature Microbiology

Experimental evolution of Pseudomonas aeruginosa shows that the population is more vulnerable to invading cheaters in a spatially extended system due to a higher level of cooperation.

Nature

Looking for a postdoc in experimental evolution? You're very welcome to apply to this position in my group, at University Paris-Saclay.

The goal is to study the evolutionary and plastic response of the transcriptome to stable vs fluctuating environments, in the model fungus Zymoseptoria tritici.

The full ad: http://www.egce.cnrs-gif.fr/wp-content/uploads/2023/08/Ad_EN_1.3.pdf

The application website:
https://emploi.cnrs.fr/Offres/CDD/UMR9191-ARNLER-004/Default.aspx?lang=EN

#postdoc #ExperimentalEvolution #PhenotypicPlasticity
@joboffersecoevo
@jobsecoevo

Proud to have contributed to this project, in which we found a drug target in Babesia #parasites using #ExperimentalEvolution. First author @Caroline_Keroack is a rising star. https://www.biorxiv.org/content/10.1101/2023.06.13.544849v1