https://doi.org/10.1016/j.cub.2025.10.043
When your body turns your DNA into one of many alternate protein forms, it uses this finely tuned biomachinery for a rope dance with the mRNA strand to carry out very coordinated cuts and joins.
Absolutely incredible to see it animated with this level of detail :0
#RNA #spliceosome #structuralbiology #animation #exons #introns #alessoninthelariat
Study of slowly #evolving 'living fossils' reveals key #genetic insights.
#gars #Lepisosteidae #DNA_repair #exons #genomics
https://phys.org/news/2024-03-slowly-evolving-fossils-reveals-key.html
In 1859, Charles Darwin coined the term "living fossils" to describe organisms that show little species diversity or physical differences from their ancestors in the fossil record. In a new study, Yale researchers provide the first evidence of a biological mechanism that explains how living fossils occur in nature.
Finished up another Wikipedia article, this time on biochemist Susan "Sue" Berget.
One of several women responsible for the discovery of split genes, all of whom were given little credit and the Nobel Prize for the research went to the two male professors involved and none of the postdoctoral fellows and collaborator professors who happened to be women.
Since, she's gone on to do amazing work on exons and variable splicing.