🗞️ Congrats to @OlivierSupplisson from the team for his impressive analysis of massive #HPV data (362,963 tests performed in France from 2020 to 2023) published in #Eurosurveillance.
🔎 This is analysis at the #postcode level (!) was made using hierarchical #Bayesian models.
It has implications for #screening as he shows a risk of systematic inflation of high-risk HPV infection prevalence.
Maps also show increased prevalence for #HPV16 and #HPV18 in some areas
BA.2.86 & its descendant, JN.1, of #SARSCoV2 dominate the winter wave. But why?
Using live virus neutralisation & sera taken in fall 2023 we found clear neutralisation escape against recent variants but no specific escape for BA.2.86/JN.1.
➡️ Neutralisation escape doesn't seem to explain the JN.1 increase. Further studies may find the driving force instead.
New publication out:
https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2024.29.2.2300740
Congrats to Lara and Barbara!
#CharitéVirology #Eurosurveillance @ChariteBerlin
Variant BA.2.86 and its descendant, JN.1, of SARS-CoV-2 are rising in incidence across Europe and globally. We isolated recent JN.1, BA.2.86, EG.5, XBB.1.5 and earlier variants. We tested live virus neutralisation of sera taken in September 2023 from vaccinated and exposed healthy persons (n = 39). We found clear neutralisation escape against recent variants but no specific pronounced escape for BA.2.86 or JN.1. Neutralisation escape corresponds to recent variant predominance but may not be causative of the recent upsurge in JN.1 incidence.
The result of fruitful joint work :
"...Establishment of West Nile virus in a large urban area in Europe (= #Berlin )".
https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2023.28.48.2300258
#WNV #Arbovirus #CharitéVirology #Eurosurveillance
@ChariteBerlin
Background West Nile virus (WNV), found in Berlin in birds since 2018 and humans since 2019, is a mosquito-borne virus that can manifest in humans as West Nile fever (WNF) or neuroinvasive disease (WNND). However, human WNV infections and associated disease are likely underdiagnosed. Aim We aimed to identify and genetically characterise WNV infections in humans and mosquitoes in Berlin. Methods We investigated acute WNV infection cases reported to the State Office for Health and Social Affairs Berlin in 2021 and analysed cerebrospinal fluid (CSF) samples from patients with encephalitis of unknown aetiology (n = 489) for the presence of WNV. Mosquitoes were trapped at identified potential exposure sites of cases and examined for WNV infection. Results West Nile virus was isolated and sequenced from a blood donor with WNF, a symptomatic patient with WNND and a WNND case retrospectively identified from testing CSF. All cases occurred in 2021 and had no history of travel 14 days prior to symptom onset (incubation period of the disease). We detected WNV in Culex pipiens mosquitoes sampled at the exposure site of one case in 2021, and in 2022. Genome analyses revealed a monophyletic Berlin-specific virus clade in which two enzootic mosquito-associated variants can be delineated based on tree topology and presence of single nucleotide variants. Both variants have highly identical counterparts in human cases indicating local acquisition of infection. Conclusion Our study provides evidence that autochthonous WNV lineage 2 infections occurred in Berlin and the virus has established an endemic maintenance cycle.
1/ Three papers in latest #Eurosurveillance issue (03 Aug 2023) are on outbreaks of highly pathogenic #AvianInfluenza A(#H5N1) virus infection in animals. #HPAI
"Highly pathogenic avian influenza A(H5N1) virus infection on multiple fur farms in the South & Central Ostrobothnia regions of Finland, July 2023"
▶️ First reported on 14 July, an outbreak of avian influenza among farmed foxes, minks & raccoon dogs
▶️ Up to 27 July, animals on 20 farms have been affected
đź”—: https://doi.org/10.2807/1560-7917.ES.2023.28.31.2300400
Since mid-July 2023, an outbreak caused by highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.4b genotype BB is ongoing among farmed animals in South and Central Ostrobothnia, Finland. Infections in foxes, American minks and raccoon dogs have been confirmed on 20 farms. Genetic analysis suggests introductions from wild birds scavenging for food in farm areas. Investigations point to direct transmission between animals. While no human infections have been detected, control measures are being implemented to limit spread and human exposure.
Short article in #Eurosurveillance about #dengue outbreaks in France in 2022, showing the large distribution of human cases in southern #France 🇲🇫 all along the season of activity of #Aedesalbopictus 🦟 #moustiquetigre
👉 https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.44.2200818?emailalert=true
#Eurosurveillance, published by @ECDC_EU
, is seeking an interim #AssistantEditor to support with such tasks as:
Providing high quality #editing
#Proofreading articles
Processing articles
Performing editorial tasks
Learn more and apply: https://bit.ly/31bCKVE
Vår vision är att alla trivs och är engagerade på jobbet. Vi tycker om att arbeta med människor och vi har lång erfarenhet av att hjälpa människor att hitta spännande karriärvägar. Vi har ett stort nätverk av företag inom många branscher som söker nya kollegor. Hos oss hittar du jobb på storbanker, multinationella IT-bolag, världsledande telecomföretag, hälsoorganisationer, statliga myndigheter och mindre privata företag. <title>Editor with an eye for details to EU Agency – Perido</title> <link rel='dns-prefetch' href='//fonts.googleapis.com' /> <link rel='dns-prefetch' href='//s.w.org' /> <link rel=
Ecology & Evolution of Health
Victor M. Corman
Ed Hill
Giuseppe Michieli
Guillaume Lacour (Dr. moustik)
redfrog