#RaphaelMechoulam, the father of 🌱 #cannabis #research, passed away on March 10, 2023, at 92 years of age. In early 1960, he was the first to reveal the structure of #cannabidiol (#CBD) and delta 9-#tetrahydrocannabinol (#THC), molecules now used worldwide as #medicine.1,2 In addition, Professor #Mechoulam and his research group identified the #endocannabinoidsystem, a #biologicalsystem with #endogenous #neurotransmitters that bind to specific #receptors ... https://pmc.ncbi.nlm.nih.gov/articles/PMC10288473/
Embryo Development Linked to a 500-Million-Year-Old Viral Infection

A critical early stage of embryonic development has been linked to a virus that mixed with the ancestral DNA of complex organisms like ourselves more than 500 million years ago.

ScienceAlert
Using a sophisticated #optogenetic approach, the researchers have discovered a previously unknown #endogenous acid sensor in #plant #cells. And they have discovered in the guard cells of leaves that there is a #calcium store that plays an important role in processing #proton signals in #cellular responses.
#Biology #sflorg
https://www.sflorg.com/2023/12/bio12152301.html
Acid Sensor and Calcium Store Discovered in Plants

When plants are infected by pathogens, suffer from a lack of water or have to react to other external stimuli

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Explore the #evolution of plant signaling networks and the strategies that #plants use to integrate #environmental and #endogenous #signals in a new #OpenAccess #JIPB paper by Diao et al. https://onlinelibrary.wiley.com/doi/10.1111/jipb.13554
Natural High: Endogenous Psychedelics in the Gut and Brain
Psychedelics are evolutionarily ancient compounds produced by fungi, plants, and microbes. Humans also synthesize psychedelics. Researchers want to know how and why.
https://www.the-scientist.com/features/natural-high-endogenous-psychedelics-in-the-gut-and-brain-71301 #Endogenous #Psychedelics #Gut #Brain #tryptophan #serotonin #melatonin #human
Natural High: Endogenous Psychedelics in the Gut and Brain

Psychedelics are evolutionarily ancient compounds produced by fungi, plants, and microbes. Humans also synthesize psychedelics. Researchers want to know how and why.

The Scientist Magazine®
High Time: The Roles of Endogenous Psychedelics
Steven Barker is on a forty-seven-year-long journey to understand the mind-blowing science of psychedelics.
His research career spans almost five decades, during which he studied how hallucinogens work, whether humans produce psychedelic compounds, and what role they may play in neuroprotection, psychiatric disorders, perception, creativity, imagination, dream states, and near-death experiences.
https://www.the-scientist.com/ts-digest/issue/the-roles-of-endogenous-psychedelics-18-2#high-time-the-roles-of-endogenous-psychedelics-71199 #endogenous #psychedelics #hallucinogens #neuroprotection
TS Digest Issue | August 2023 | The Roles of Endogenous Psychedelics

Researchers begin to understand the mind-blowing science of psychedelics.

The Scientist Magazine®
#endogenous #cannabinoids and #endogenous #opioids (#endorphins), are both major parts of our physiologic systems, including central nervous system, immune system #MolecularReality #HealthScience #SharedFacts

Last preparations for my talk in symposium S36 "Transformations of visual representations from retina to cortex" at #GoeMe23.

I will explore a nature-nurture transform that underlies the emergence of reliable, mature representations of visual angles.

Many thanks to Dr. Helene Schreyer & Dr. Norma Kühn @nkkuhn for organizing such a great lineup and inviting me as early career speaker!
Friday, 14.40 in Hall 104

#vision #selforganization #endogenous

#Oxytocin's role in out-group violence and discrimination is well-documented. Oxytocin makes everything an in-group member says or does seem wonderful, socially acceptable and, somehow, correct. Those "others," however, are given the exact opposite treatment - the "others" are a threat, socially undesirable, and patently incorrect in all their thoughts and actions.

Reference:
Sapolsky, R. M. (2017). Behave: The biology of humans at our best and worst. Penguin. #endogenous #drugs

#Drugs scholars,

Let's discuss #endogenous chemicals and the links between #addiction, addictive #behavior, and #discrimination.

For instance, consider the role #oxytocin plays in pro-social and anti-social behavior based on the activation of social and psychological attachment or repulsion. Oxytocin influences behavior toward both in-group and out-group members, lending itself to a neuro-chemical reward pathway towards cruel behaviors visited upon members of the out-group.