Stephan HackerDec 3

Insightful talk by Dieuwertje Streefkerk at #NWOCHAINS. She talked about their synthetic work on stereochemically defined sulfur(VI) electrophiles and their use as #CovalentInhibitors on the example of chymotrypsin inhibition.

https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.202415873
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201915519
#Chemistry #ChemBio #Electrophiles

Stephan HackerDec 3
Insightful talk by Dieuwertje Streefkerk at #NWOCHAINS. She talked about their synthetic work on stereochemically defined sulfur(VI) electrophiles and their use as #CovalentInhibitors on the example of chymotrypsin inhibition. onlinelibrary.wiley.com/doi/full/10.... #ChemSky #ChemBio #Electrophiles
Stephan HackerNov 21
Insightful presentation by Minjia Tan at #ISCPDD. She talked about her group’s research into the use of the photoactivated ortho-nitrobenzyl alcohol (oNBA) reactive group and its application to studying protein complexes in live cells.
https://onlinelibrary.wiley.com/doi/10.1002/anie.202507254
#ChemSky #ChemBio #Electrophiles #Crosslinking #XLMS
Show threadStephan HackerOct 30
A big thank you also to Stacey Paiva and her team at Nature Chemistry for their support and patience with me. #CovalentInhibitor #DrugDiscovery #Proteomics #ChemicalProteomics #MassSpectrometry #Electrophiles #ProudPI #AcademicLife #NewPublication #Chemistry #ChemBio #ChemSky (6/7)
Show threadStephan HackerOct 30

A big thank you also to Stacey Paiva and her team at Nature Chemistry for their support and patience with me.

#CovalentInhibitor #DrugDiscovery #Proteomics #ChemicalProteomics #MassSpectrometry #Electrophiles #ProudPI #AcademicLife #NewPublication #Chemistry #ChemBio
(6/7)