[Electrical stimulation on epileptic tissue] Westin et al.: “Stimulation over the seizure onset zone reduced background activity and interictal spike rate.”
doi.org/10.1016/j.clinph.2018.10.009
@karolinskainst
#ElectricalStimulation #Epilepsy #ClinicalNeuroph
Electro Shock and E-Stim Devices: A Deep Dive into History, Uses, and Modern Practices MISTRESS MARA MENOCI
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Researchers developed a new rehab system for #stroke patients. It combines an #exoskeleton with #ElectricalStimulation to restore arm and hand movement. A #DigitalTwin customizes support, helping patients train independently: http://go.tum.de/512851
#MedTech
📷S.Bauer
Personalised training after a stroke
Researchers at TUM have built a system consisting of an exoskeleton and electrical stimulation to help people learn to grasp again after a stroke.
Long-term stimulation by implanted pacemaker enables non-atrophic treatment of bilateral vocal fold paresis in a human-like animal model - Scientific Reports
A wide variety of treatments have been developed to improve respiratory function and quality of life in patients with bilateral vocal fold paresis (BVFP). One experimental method is the electrical activation of the posterior cricoarytenoid (PCA) muscle with a laryngeal pacemaker (LP) to open the vocal folds. We used an ovine (sheep) model of unilateral VFP to study the long-term effects of functional electrical stimulation on the PCA muscles. The left recurrent laryngeal nerve was cryo-damaged in all animals and an LP was implanted except for the controls. After a reinnervation phase of six months, animals were pooled into groups that received either no treatment, implantation of an LP only, or implantation of an LP and six months of stimulation with different duty cycles. Automated image analysis of fluorescently stained PCA cross-sections was performed to assess relevant muscle characteristics. We observed a fast-to-slow fibre type shift in response to nerve damage and stimulation, but no complete conversion to a slow-twitch-muscle. Fibre size, proportion of hybrid fibres, and intramuscular collagen content were not substantially altered by the stimulation. These results demonstrate that 30 Hz burst stimulation with duty cycles of 40% and 70% did not induce PCA atrophy or fibrosis. Thus, long-term stimulation with an LP is a promising approach for treating BVFP in humans without compromising muscle conditions.
Tadonic the Flautulent
Clinical Neurophysiology
Maramenoci.com
Technische Universität München
Leibniz-HKI