Joanna MaselSep 6, 2024
Our latest paper https://elifesciences.org/articles/87335
directly measures the #EffectivePopulationSize that matters to #NearlyNeutralTheory / #DriftBarrier theory, as the degree to which #CodonBias differs from expectations from GC content. Surprisingly, stronger #NaturalSelection -> higher #IntrinsicStructuralDisorder proteins
#MolecularEvolution #PopulationGenetics #EvolgenPaper 1/
The protein domains of vertebrate species in which selection is more effective have greater intrinsic structural disorder

Proteins evolve more intrinsic structural disorder under more effective selection, with selection assessed via a novel metric of codon adaptation.

eLife
Nicolas BierneAug 10, 2023

#PopGen #EvolMol #ThalerConference #MustWatch #AlternativeSplicing #SplicingErrors #DriftBarrier Amazing talk by @duret_lbbe here on the SEEM youtube channel 👇

https://ecoevo.social/@couplingdmi/110860290160070455

Nicolas Bierne (@couplingdmi@ecoevo.social)

Amazing conference by Laurent Duret, meticulously demystifying the alternative splicing fad. It's all about splicing errors, folks! Now on youtube here: https://youtu.be/qPKkjzeLqBU Should be watch by every students, every molecular biologists ...

ecoevo.social