Vaccination against microbiota motility protects mice from the detrimental impact of dietary emulsifier consumption

Bacterial flagellin is a key mediator of detrimental impacts on intestinal health caused by dietary emulsifier. This study shows that immunizing mice against flagellin can prevent emulsifier-induced changes in microbiota pro-inflammatory potential, microbiota encroachment, as well as deleterious consequences such as intestinal inflammation and metabolic deregulation.