Finally got nixos dendritic to work! so excited! May be working on a tutorial soon (if i dont forget lmao)
Finally got nixos dendritic to work! so excited! May be working on a tutorial soon (if i dont forget lmao)
🧠 New preprint by Lee et al.: Fast dendritic excitations primarily mediate #backpropagation in #CA1 pyramidal #neurons during #behavior
Using kHz #VoltageImaging across the full #dendritic tree, they show that fast dendritic spikes are usually driven by somatic #bAPs, not independently initiated. #bAP propagation into apical dendrites is contin. modulated by pre-spike dendritic voltage & can trigger slower plateau potentials linked to complex spikes.
🧠 Pastorelli et al. (2025) present a "simplified two-compartment #neuron with #CalciumDynamics capturing #brain-state-specific apical-amplification, -isolation and -drive". This Ca-#AdEx model replicates distinct #dendritic mechanisms across wakefulness, #NREM & #REM sleep using a compact ThetaPlanes transfer function. Cool implementation using the #NESTsimulator 💻!
#OpenSLS update: Generation of model #tissues with #dendritic #vascular networks via sacrificial #laser-sintered #carbohydrate templates: https://rdcu.be/b5tHy
Hardware designs: https://github.com/MillerLabFTW/OpenSLS
-R4: specialty powders for biomaterials research
-R3: nylon & wax #SLS
-#Python add-on for #Blender to generate bifurcating vascular structures
#DIYbio #OpenSource #lab #3Dprinting #bioprinter #laser #hydrogel #instruments