AI tool targets RNA structures to unravel secrets of the dark genome

We mapped the human genome decades ago, but most of it is still a black box. Now, UNSW scientists have developed a tool to peer inside and what they find could reshape how we think about disease.

Phys.org

Dark Genome Awake: Proteins Crash Biology Party, Medicine Panics

#DarkGenome #ScienceSatire #PharmaFollies #ProteinParty #UnchartedBiology By: TheJestPress.com **Researchers Discover “Dark Genome” Full of Mysterious Proteins, Pharmaceutical Industry Grumbles Over Even MORE Homework** Move over dark matter—the dark genome just crashed the mystery party, and it brought some truly unsettling plus-ones: “dark proteins.” Previously thought to be the genetic equivalent of…

http://thejestpress.com/2025/07/31/dark-genome-awake-proteins-crash-biology-party-medicine-panics/?utm_source=mastodon&utm_medium=jetpack_social

Dark Genome Awake: Proteins Crash Biology Party, Medicine Panics

#DarkGenome #ScienceSatire #PharmaFollies #ProteinParty #UnchartedBiology By: TheJestPress.com **Researchers Discover “Dark Genome” Full of Mysterious Proteins, Pharmaceutical Industry Grumbles Ove…

THEJESTPRESS.COM
Bei einigen neurologischen Entwicklungsstörungen besteht häufig eine Mutation im Gen RNU4-2, zeigen Forschende in Nature Medicine. Neue Erkenntnis dank Erforschung des #DarkGenome. Experten sehen wichtigen Schritt für die Diagnostik: https://www.sciencemediacenter.de/alle-angebote/research-in-context/details/news/mutationen-im-rnu4-2-gen-loesen-entwicklungsstoerungen-aus?mtm_campaign=mastodon&mtm_kwd=mutation-gen-entwicklungsstoerungen
Mutationen im RNU4-2-Gen lösen Entwicklungsstörungen aus

Bei einigen neurologischen Entwicklungsstörungen besteht laut Studie häufig eine Mutation im Gen RNU4-2. Experten sehen wichtigen Schritt für die Diagnostik:

Scientists Reveal Structure of Ancient Virus-Like Genetic Element | Sci.News

The Long Interspersed Element-1 (LINE-1) retrotransposon is an ‘ancient genetic parasite’ that has written around one third of the human genome through a ‘copy-and-paste’ mechanism.

Sci.News: Breaking Science News
Dark Genome Discovery: Researchers Reveal “Ancient Genetic Parasite” Implicated in Human Diseases

Understanding the mechanism of LINE-1 is key to developing potential new treatments for cancer, autoimmune disorders, neurodegeneration, and even aging. Research published on December 14 in Nature sheds light on a small part of the so-called “dark genome” — the 98 percent of the human genome whos

SciTechDaily

Clearly, there is still much to learn about this corner of the dark genome defined by HEATR5 proteins and their co-factors.

#Biorxiv #Preprint #MembraneTraffic #DarkGenome #DarkProteome #RareDisease #AlphaFold #AlphaFold2 #ProteinPrediction #Golgi #Clathrin #CellBiology #biochemistry #Bioscience

@bbruneau We are glad you are here Benoit- #DevBiol #Heart #Chromatin #DarkGenome