Creatine is having a viral moment for mitigating sleep deprivation.
Maybe some folks with Long COVID or ME/CFS will be interested in this paper https://www.nature.com/articles/s41598-024-54249-9
Our outcomes show that administering a high single dose of creatine can partially reverse metabolic alterations and fatigue-related cognitive deterioration.
At 0.35 g creatine/kg body they found:
Creatine significantly reduced fatigue
and
The crucial factor appears to be the increased energy demand of the neuronal cells in combination with an increased extracellular creatine availability
This was a small but high quality study in 2024.
#creatine #fatigue #health