Mastodawn

Bernhard Schermer Aug 6, 2024

📣 Just heard that the Cilia2024 conference is almost fully booked! 😊

Hurry and grab the last on-site spots for the world's biggest cilia meeting in beautiful Dublin!

Last-minute industry sponsors are welcome!

Online participation in this hybrid meeting is, of course, not limited.

Webpage: https://cilia2024.ie/

#Cilia2024 #Ciliopathies #RareDisease #ADPKD #PCD #BBS #NPHP #Centrosome #Centriole #CellBiology #DevelopmentalBiology #Nephrology #Neurology #EMBO @cilia @cellbiology

Cilia2024

Lukas VFN 🇪🇺Apr 11, 2024

Scientists reconstruct assembly of the human #centriole, image by image, for the first time
https://phys.org/news/2024-04-scientists-reconstruct-human-centriole-image.html

Time-series reconstruction of the molecular architecture of human centriole assembly: Marine Laporte et al. https://www.sciencedirect.com/science/article/pii/S0092867424003167

"This #organelle is essential to the organization of the cell skeleton... Organelle genesis proceeds according to a precise sequence of successive protein recruitment events."

Scientists reconstruct assembly of the human centriole, image by image, for the first time

Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles." Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.

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Mill_lab Jan 16, 2024

We close with Dan Dodd (Mill lab, MRC HGU) on unique #cilia & #centriole-specific functions for #tubulin isotype TUBB4B with dominant negative roles in motile & non-motile #ciliopathies. New insights from Alan Brown & Jeff Ti Labs. Deep read: www.medrxiv.org/content/10.1... #ukcilia2024 6/8

PLOS Biology Nov 21, 2023

How do mother centrioles make only one daughter centriole? @JRafflab shows that PLK4, master regulator of #centriole biogenesis, may form a 2-component #Turing-system to allow it to break symmetry & form a single site for daughter assembly #PLOSBiology https://plos.io/46ksfyE

A simple Turing reaction–diffusion model explains how PLK4 breaks symmetry during centriole duplication and assembly

How do mother centrioles generate only a single daughter centriole? This study shows that Polo-like kinase 4 (PLK4), the master regulator of centriole biogenesis, may form a simple two-component Turing-system to allow it to break symmetry and form a single site for daughter centriole assembly.

The EMBO Journal Nov 21, 2023

Next #RefereedPreprint c/o @ReviewCommons published in @embojournal
Gönczy et al @epfl_en show that #centriole elimination during C. #elegans #oogenesis occurs in two steps, initiated by loss of central tube protein SAS-1
https://www.embopress.org/doi/full/10.15252/embj.2023115076

Mill_lab Sep 1, 2023

Two+ weeks 🚨 19/09/2023 15:00-17:15 BST 🚨until our 45th BSCB GenSoc UK Cilia Network e-symposium- free and open to all! >1260 folks already registered, this is the #cilia #centriole place to be! Not on my list already, sign up here: https://www.eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835

We have all good things lined-up: #GeneRegulatoryNetworks, #Signalling, mind-blowing #cryoET protein ID, #OrganelleProteomics in #neurons AND everything #tubulin! Join us...

BSCB GenSoc UK Cilia Network e-Symposia Series

Eventbrite

Bernhard Schermer Jul 15, 2023

Sharing this announcement on the fediverse. Unsure if Elif has joined Mastodon yet…

Some of us might see this as the basal body meeting 😉

@cilia
#Centrosome2023
#cilia #centrosome #centriole #Embo #EmboWorkshop #Science #zilien #RareDisease #ScienceMastodon #Zentrosom #developmentalbiology #biology @nephrology #CellBiology #Ciliopathy

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Bernhard Schermer Jan 20, 2023

@Mill_lab

Wonderful!
For more sleeps ...
🙂

#cilia #ciliopathy #RareDiseases #centrosome #centriole #CellBiology #DevelopmentalBiology #DevBio
@cilia

Mill_lab Jan 17, 2023

Our first session of 2023 looking to keep virtual communities connected- our 42nd BSCB GenoSoc UK Cilia Network e-symposium 24/01/2023 15:00-17:15 free & open to all #cilia & #centriole fans! Register if not on our list already: https://eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835

We kick off with 6 sensational speakers who were poster prize winners from EMBO Cilia2022 meeting to kick of the new year- #cilia, #centriolarsatellites, #ciliopathies! Come see our plans for 2023...