A novel analytical method that enables scientists to track and quantify trace amounts of metal-based cancer drugs within specific compartments of living cells without requiring the destruction of the cells first.
#AnalyticalChemistry #Radiochemistry #Oncology #CellBiology #sflorg
https://www.sflorg.com/2026/04/chm04172601.html
New technique maps cancer drug uptake inside living cells

A new analytical method could improve how cancer treatments are designed

Cellular senescence is a biological stress response where cells cease dividing but do not die, instead lingering in tissue and emitting a toxic cocktail of inflammatory signals. In the liver, immune cells known as macrophages can enter this "zombie" state, continuously accumulating and driving the chronic inflammation associated with both aging and fatty liver disease.
#CellBiology #Immunology #Hepatology #Gerontology #MolecularBiology #sflorg
https://www.sflorg.com/2026/04/cbio04162602.html
UCLA scientists identify zombie immune cells as a driver of fatty liver disease, inflammation and aging

The study found that excess dietary cholesterol, not just aging alone, can push these immune cells into a permanently inflamed state, suggesting that

A breakthrough class of spontaneously blinking fluorescent dyes that enable ultra-detailed, super-resolution microscopy of living cells without causing cellular damage.
#CellBiology #Oncology #Bioengineering #ChemicalBiology #sflorg
https://www.sflorg.com/2026/04/cbio04162601.html
New imaging tools help cancer researchers see inside living cells

OHSU scientist helps develop imaging strategy that unlocks next-generation dyes to study how cancer cells grow, move, change in real time

Cell membranes serve as more than just structural scaffolds and environmental barriers; they actively influence the behavior and signaling processes of the protein receptors embedded within them. Specifically, the lipid composition of a membrane can directly alter the functional state of critical cellular components like the epidermal growth factor receptor (EGFR).
#Biochemistry #CellBiology #BiophysicalChemistry #Oncology #sflorg
https://www.sflorg.com/2026/04/bchm04162601.html
MIT study reveals a new role for cell membranes

Long thought to be mainly a structural support, the cell membrane also influences how cells respond to signals and may contribute to the growth of can

#MitoCatch is an advanced cellular delivery system designed to transplant healthy donor mitochondria directly into diseased or damaged cells. It acts as a targeted therapy to restore vital energy management in cells suffering from mitochondrial dysfunction.
#MolecularBiology #CellBiology #Neuroscience #MitochondrialMedicine #sflorg
https://www.sflorg.com/2026/04/mbio04152601.html
MitoCatch delivers healthy mitochondria to diseased cells

MitoCatch overcomes the long-standing biological obstacle of targeted delivery without triggering a detectable immune response

Postdoc Positions - Structural Biology, Biochemistry, Cell Biology

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Neurons actively maintain and utilize lipid reserves in the form of lipid droplets for cellular energy and structural maintenance. This discovery fundamentally challenges the long-held scientific consensus that neurons rely almost exclusively on glucose to power their high metabolic demands.
#Neuroscience #CellBiology #Biochemistry #MetabolicEndocrinology #sflorg
https://www.sflorg.com/2026/04/ns04142601.html
Neurons store and burn lipids, not just glucose

A new study shows that lipid droplets are crucial for neuronal function and synaptic activity.

Lab Manager / Research Associate -- Joiner Lab, Univ. of Cincinnati

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