🧬 ✂️ 🌱 Call for papers for our upcoming special issue on
#Cas12 mediated
#GenomeEditing in
#plantscience! Submission deadline November 30, 2025.
@wileyplantsci
(Thanks to our publisher, Wiley, for the spiffy graphic)
Learn more here:
https://onlinelibrary.wiley.com/page/journal/17447909/homepage/call-for-papers/si-2025-000295#botanyResearchers at the Broad Institute of MIT and Harvard and Cyrus Biotechnology have now
#engineered two
#CRISPR nucleases,
#Cas9 and
#Cas12, to mask them from the
#immune system.
#Biotechnology #Biomedical #sflorghttps://www.sflorg.com/2025/01/biot01092501.html
Scientists engineer CRISPR enzymes that evade the immune system
The new genome-editing tools could lead to safer, more efficient gene therapies.
To TnpB or not TnpB? #Cas12 is the answer | Nature Chemical Biology
https://www.nature.com/articles/s41589-022-01243-9
To TnpB or not TnpB? Cas12 is the answer - Nature Chemical Biology
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA
#cas #cas12 #crispr
https://www.nature.com/articles/s41586-022-05559-3
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA - Nature
RNA targeting by the Sulfuricurvum type V single-effector nuclease SuCas12a2 drives abortive infection through non-specific cleavage of double-stranded DNA—after recognition of an RNA target through an activating protospacer-flanking sequence, SuCas12a2 efficiently degrades ssRNA, ssDNA and dsDNA.
JIPB
Scientific Frontline
Vivek Mutalik