As a medical school professor, I remind students: weight-loss drugs aren't just "appetite meds." They're metabolic signaling.

A new proof-of-concept RCT in The Lancet (EClinicalMedicine) tested dapiglutide—a dual GLP-1 + GLP-2 agonist—once weekly for 12 weeks in adults with obesity (n=54).

Results (relative bodyweight change):
• Placebo: −2.2%
• Dapiglutide 6 mg: −4.3%
(Estimated treatm...
#obesity #GLP1 #metabolichealth #insulinresistance #cardiometabolic
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00048-9/fulltext

Long-term use of melatonin supplements linked to higher risk of heart failure and death

Long-term use of melatonin supplements, often used to promote sleep and address insomnia, was associated with a higher…
#NewsBeep #News #Topstories #blood #Cardiometabolic #chronic #CT #GeneralMedicine #Headlines #heart #HeartFailure #Hormone #insomnia #JetLag #Medicine #melatonin #NervousSystem #pH #Research #sleep #stroke #supplements #TopStories
https://www.newsbeep.com/226424/

#sphingolipids are increasingly recognised as #biomarkers of #cardiometabolic #health.

The SphingoHIIT, a RCT, showed that a single #hiit session does not alter blood sphingolipid levels in healthy young adults, under tightly controlled conditions (diet, menstrual timing, multi‑timepoint sampling).

This is an interesting feature for potential biomarkers of cardiometabolic risk.

Congrats to Dr Thomas Angst on his successful doctoral thesis completion!

https://www.csbj.org/article/S2001-0370(25)00268-5/fulltext

Mediterranean diet wins on weight but misses on memory in diverse aging population

Adopting a Mediterrane…
#dining #cooking #diet #food #MediterraneanDiet #Adipose #aging #blood #bloodpressure #BRAIN #Cardiometabolic #Cognitivefunction #dementia #drugs #HbA1c #insulin #Medicine #Mediterranean #obesity #OliveOil #pandemic #physicalactivity #Research #Vegetables #weightloss
https://www.diningandcooking.com/2158550/mediterranean-diet-wins-on-weight-but-misses-on-memory-in-diverse-aging-population/

☕️ New research reveals that moderate coffee consumption can significantly reduce the risk of multiple cardiometabolic diseases! 🌍❤️💚 This exciting finding highlights the potential health benefits of enjoying that daily cup of joe. ☕️✨ #CoffeeHealth #Cardiometabolic #Wellness

🔗 https://www.sci.news/medicine/moderate-coffee-consumption-risk-multiple-cardiometabolic-diseases-13272.html

Study findings suggest that consuming raw white garlic can significantly improve specific cardiometabolic biomarkers, including lowering total/serum cholesterol, reducing triglyceride levels, and enhancing high-density lipoprotein (HDL) cholesterol.

#garlichealth #hearthealth #cholesterol #triglycerides #cardiometabolic #naturalremedies #nutrition #wellness #healthyliving #garlicbenefits #garlic

https://www.news-medical.net/news/20240908/Raw-white-garlic-shows-promise-in-boosting-heart-health-and-reducing-disease-risks.aspx

#AntiInflammatory #Diet and #Dementia in #OlderAdults With #Cardiometabolic #Diseases

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822212