I hope everyone's watching #CancerDetectives on Channel 4!
My team has sweated over various aspects of this. It's a big passion project, my colleague's second baby, and hopefully will help more people understand what it means to do #CancerResearch today, and indeed what it means to have cancer now, compared to some decades ago.

#channel4 #cancer #cancerVaccines #BrainTumours #LiquidBiopsy #cancerOfUnknownPrimary #LungCancer #P53 #liFraumeni #5GTrial #MILITrial #DETECTION2Trial #CancerResearchUK

🧬 Cancer vaccines aren’t science fiction anymore, they’re reshaping treatment in 2025.

From mRNA breakthroughs to personalized therapies, cancer vaccines are changing how doctors fight cancer. Our latest guide explores how these innovations are improving survival, reducing relapse, and offering new hope to patients and families.

Explore more👉 https://blog.banishcancer.org/updates-on-cancer-vaccines-progress-and-perspectives-2025/

#CancerVaccines #Oncology #Immunotherapy #PersonalizedMedicine #MRNA #BanishCancer

A Phase 1 clinical trial on personalized #CancerVaccines for renal carcinoma reports promising results.

After 40 months, none of the 9 patients showed detectable recurrence. The approach involves sequencing tumor samples post-surgery to develop patient-specific vaccines, training the immune system to recognize and eliminate cancer cells.
Further studies are required, but these findings suggest potential clinical applications.

📎 https://www.nature.com/articles/s41586-024-08507-5

#cancer #vaccines #bioinformatics

A neoantigen vaccine generates antitumour immunity in renal cell carcinoma - Nature

A phase I trial of a neoantigen-targeting personalized cancer vaccine led to durable and polyfunctional T cell responses and antitumour recognition, and was associated with no recurrence in patients with high-risk clear cell renal cell carcinoma.

Nature

Cancer vaccines show promise
https://www.economist.com/science-and-technology/2025/01/01/cancer-vaccines-are-showing-promise-at-last
non-paywalled: https://archive.fo/ncAYX

Comment: revolutionary

* trials: skin, brain, lung tumors
* possible w/i 6 wk due to mRNA vaccines

https://en.wikipedia.org/wiki/MRNA_vaccine
* uses fragment (cloned copy) of messenger RNA (mRNA)
* injected; stimulates adaptive immune response
* body identifies/destroys corresponding pathogen (SARS-Cov-2: COVID-19 ...) or cancer cells

#cancer #cancervaccines #vaccines #mRNA #mRNAvaccines #immunity #ImmunoTherapy #miRNA

Cancer vaccines are showing promise at last

Trials are under way against skin, brain and lung tumours

The Economist