Chromatin remodeling tied to altered splicing in autism model

https://www.spectrumnews.org/news/chromatin-remodeling-tied-to-altered-splicing-in-autism-model/

#bioinformatics #geneexpression #valproicacid #epigenetics #sequencing #chromatin #synapses #autism #News #CHD8

CHD8 mutation in 33 mouse strains yields range of traits

https://www.spectrumnews.org/news/chd8-mutation-in-33-mouse-strains-yields-range-of-traits/

#macrocephaly #mousemodels #anxiety #autism #News #CHD8

Hoi, ben hierheen verhuisd van een server, m.sclo.nl, die er mee stopt volgende week. Was er net een maand. Kijken of het allemaal wil lukken. Nee, dus, dan maar opnieuw beginnen.
Ben, nog steeds, Renée.😋 Getrouwd, 2 dochters, 2 kleinkinderen, 1 man. Ik doe veel aan fotografie, hou van muziek, metal tot Moldau, humor, kan niet tegen onrecht, racisme e.a. onzin. 🙋🏻‍♀️🌺
Foto van kleinzoon Stijn (6). Onder de indruk van een #Notenkraker bij Intratuin
Stijn heeft een vrij onbekend syndroom #CHD8

Flexible genomic architecture undergoes major redesigns during cerebellum development

https://www.spectrumnews.org/news/flexible-genomic-architecture-undergoes-major-redesigns-during-cerebellum-development/

#cerebellum #chromatin #autism #News #CHD8

Community Newsletter: Autism gene lists, genetic diversity in mouse models, an autism biomarker

https://www.spectrumnews.org/news/community-newsletter-autism-gene-lists-genetic-diversity-in-mouse-models-an-autism-biomarker/

#faceprocessing #mousemodels #biomarkers #community #autism #News #CHD8 #EEG

‘Double duty’ autism-linked genes upend conventional characterizations

https://www.spectrumnews.org/news/double-duty-autism-linked-genes-upend-conventional-characterizations/

#chromatin #organoids #synapses #autism #cortex #News #CHD8

Heart anomalies abound in mouse models of autism

https://www.spectrumnews.org/news/heart-anomalies-abound-in-mouse-models-of-autism/

#fragileXsyndrome #mousemodels #16p11.2 #autism #SHANK3 #News #CHD8 #FMR1

Organoids show how mutations in top autism gene may lead to brain overgrowth in people

https://www.spectrumnews.org/news/organoids-show-how-mutations-in-top-autism-gene-may-lead-to-brain-overgrowth-in-people/

#endophenotype #macrocephaly #organoids #autism #News #CHD8

Three autism-linked genes converge on tweaks to cells’ timing

https://www.spectrumnews.org/news/three-autism-linked-genes-converge-on-tweaks-to-cells-timing/

#signalingimbalance #macrocephaly #chromatin #organoids #autism #News #CHD8 #GABA

Fish, frogs, flies and other fauna in scientific firsts

https://www.spectrumnews.org/features/fish-frogs-flies-and-other-fauna-in-scientific-firsts/

#neurotransmitters #fragileXsyndrome #Drosophila #C.elegans #zebrafish #Features #language #16p11.2 #CNTNAP2 #autism #SHANK3 #sleep #CHD8 #FMR1 #gut