Mastodawn

Chemokines tend to be below the LOD in vivo for tryptic peptides, but may be observed via MHC class I & II peptide experiments.

#CCL17 (C-C motif chemokine ligand 17): Human Protein Atlas mRNA tissue distributions & GPMDB protein tissue tabbulations. #proteomics

In #Science (@sciencemagazine) this week, the Hanahan lab shows that the #RNA-binding protein #FMRP enables #tumors to evade being attacked by #CD8TCells. It does so by both suppressing #CCL17 & promoting #Tregs via #IL33 & #M2 #macrophages via #PROS1 & #ExtracellularVesicles!