#EndothelialCell ARF6 GTPase links IL-1β inflammation with TGFβ/BMP-SMAD1/5 #EndMT

EC Arf6 KO in🐭#EAE->
⏫#BBB #BloodSpinalCordBarrier
⏬T cell infiltration & demyelination
w/o altering normal immunity

Dr. Shannon Odelberg, Weiquan Zhu labs Neuron 2022
https://www.sciencedirect.com/science/article/pii/S0896627322006602