Before #cells can divide, they first need to replicate all of their #chromosomes, so that each of the daughter cells can receive a full set of #genetic material. Until now, scientists had believed that as division occurs, the #genome loses the distinctive 3D internal structure that it typically forms.
#Biomolecular #Biochemistry #Bioengineering #sflorg
https://www.sflorg.com/2025/10/bmol10172501.html
In a surprising discovery, scientists find tiny loops in the genomes of dividing cells

Enabled by a new high-resolution mapping technique, the findings overturn a long-held belief that the genome loses its 3D structure when cells divide.

#Lipids are fatty #molecules that play critical roles in cell function, including membrane structure, energy storage and nutrient absorption. Most lipids are made in a cell #organelle called the #endoplasmic reticulum, but specific lipid types are shuttled around to different parts of the cell depending on their purpose.
#Biochemistry #Biomolecular #sflorg
https://www.sflorg.com/2025/10/bchm10162501.html
The Many FACES of Lipid Research

A new technology will give unprecedented views of lipid movement inside cells

Researchers at Umeå University have identified a key #molecular player that helps #bacteria survive the hostile #environment inside the body. Their study reveals how the protein #RfaH acts as a protective shield for bacterial #genes — and points to new strategies for fighting persistent infections.
#Biomolecular #Microbiology #sflorg
https://www.sflorg.com/2025/10/bmol10162501.html
“Molecular bodyguard” helps infections persist

Persistent bacterial infections pose a major challenge in medicine

#Water is everywhere – it covers most of the earth, circulates in the human body and can be found in even the smallest #molecular niches. But what happens if water does not flow freely but is trapped in such structures?
#Chemistry #Biomolecular #MolecularScience #sflorg
https://www.sflorg.com/2025/10/chm10142502.html
Binding power of trapped water demonstrated for the first time

Longstanding topic of supra - and biomolecular chemistry clarified – Trapped water reinforces molecular bonds

This study contradicts the more traditional #evolutionary view — on island-colonizing species, whose #genomes are larger and often have more repetitive elements — and expands the scientific debate on a major puzzle in evolutionary biology: how and why does genome size change during the evolution of living beings?
#Genetics #Biology #Biomolecular #sflorg
https://www.sflorg.com/2025/10/gen10132501.html
Deciphering the mechanisms of genome size evolution

The sequencing of the genomes of a spider from the mainland

Evidence challenging the long-held assumption that #neuronal function in the #brain is solely powered by sugars has given researchers new hope of treating debilitating brain disorders.
#Biomolecular #Biomedical #Neuroscience #sflorg
https://www.sflorg.com/2025/10/bmol10012501.html
Fat particles could be key to treating metabolic brain disorders

UQ researchers have demonstrated that sugars are not the sole source of fuel for brain neurons

A Cornell-led study has revealed how a deadly form of #pancreatic #cancer enters the bloodstream, solving a long-standing mystery of how the disease spreads and identifying a promising target for therapy.
#Biomedical #Biomolecular #sflorg
https://www.sflorg.com/2025/09/bmed09242501.html
Key driver of pancreatic cancer spread identified

In other words, ALK7 gives pancreatic cancer cells both the engine to move and the tools to invade

In a mouse model of #liver #transplantation, UCLA researchers have identified #proteins that act as “protective switches” guarding the liver against damage occurring when blood supply is restored during transplantation, a process known as ischemia-reperfusion injury.
#Medical #Biomolecular #sflorg
https://www.sflorg.com/2025/09/med09242501.html
UCLA researchers find “protective switches” that may make damaged livers suitable for transplantation

Two key proteins could lead to therapies that rejuvenate suboptimal donor organs and expand the liver transplant pool

Post-doc Position in Molecular Microbiology

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv
In the march of metastasis, a #molecular trail of crumbs guides some #cancer cells from the primary #AgriculturalSciencetumor to establish new colonies within the body.
#Biomedical #Biomolecular #sflorg
https://www.sflorg.com/2025/09/bmed09172501.html
Subtle cues between cells and immune system contribute to spread of cancer

When cells in the body are threatened by pathogens or tissue damage, they secrete chemokines