🔬 New #SpectralUnmixing paper by Ashesh et al. ( @florianjug): A #DeepLearning-based framework #MicroSplit for #FluorescenceMicroscopy that separates highly overlapping #fluorophore signals directly from multiplexed #ImagingData. Improves signal separation, reduces crosstalk, & enables more accurate multi-channel #imaging w/o requiring extensive reference measurements. Can’t wait to try this out on our in vivo #2P/ #3P imaging data:

📝 https://doi.org/10.1038/s41592-026-03082-1

#Bioimaging

Deadline is this Friday 1 May to submit your research to the JCS special issue: Imaging Cell Architecture and Dynamics
#imaging #cellbiology #bioimaging https://journals.biologists.com/jcs/pages/imaging

@nfdi4bioimage started the new year with enthusiasm and many plans, and you'll find what's new, what's upcoming, and what's to read or review in our latest newsletter.

Take a look to find out about the latest developments within the @NFDI and get an overview of upcoming conferences, workshops, and publications related to #bioimaging research data management for the upcoming year.

📨 https://nfdi4bioimage.de/community-integration/newsletter/#c896618

🖼️🎥 New to BIIGLE? Join the BIIGLE4Beginners Workshop!
🗓️ Dec 11, 2025 | 14:00–16:00 CET | 🌐 Online
Learn end-to-end image & video annotation from #BioImaging – perfect for newcomers!
Register: https://www.denbi.de/training-courses-2025/1984-biigle4beginners-december-workshop-2025
#BIIGLE #ImageAnnotation #VideoAnnotation

🧬 How can AI bridge the gap between histology and spatial transcriptomics?

🔗 SegDecon bridges histology and transcriptomics through AI-based nuclei segmentation and image-informed spatial deconvolution. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.041

📚 CSBJ: https://www.csbj.org/

#SpatialTranscriptomics #Histology #Genomics #SystemsBiology #NucleiSegmentation #AI #CellBiology #TissueBiology #Bioimaging

Quantifying Electrophoresis Gel Bands with QuPath and Galaxy

Gel Electrophoresis is a staple of molecular biology, providing a way to separate DNA, RNA, or proteins by size and charge. While gels are usually interpreted visually, the ability to quantify band intensities offers much richer insights—allowing researchers to estimate product yields, verify PCR amplification, or assess protein purity.

Galaxy Training Network
Quantifying Electrophoresis Gel Bands with QuPath and Galaxy

Gel Electrophoresis is a staple of molecular biology, providing a way to separate DNA, RNA, or proteins by size and charge. While gels are usually interpreted visually, the ability to quantify band intensities offers much richer insights—allowing researchers to estimate product yields, verify PCR amplification, or assess protein purity.

Galaxy Training Network

On Day 2 of European Galaxy Days, Beatriz Serrano-Solano presented Update by the Imaging Community.
Read more: https://galaxyproject.org/community/sig/image-analysis/

@galaxyfreiburg
#imaging_community #bioimaging #EGD2025 #galaxyproject #eosc #fair #community #open_science

Amazing talk by Björn Grüning from @galaxyfreiburg at @unifreiburg and task area leader @nfdi4bioimage on the power of #Galaxy at #CoRDI2025. Cloud-deployed workflows as a basis for reuse across domains.

An example? Voronoi segmentation in #bioimaging, forest imagery & astronomy. 👏