TRACE (tetrazine release and activation by cellular enzymes) is a novel bioorthogonal chemical method that locks reactive molecules inside protective cages until they are released by enzymes specific to diseased cells.
#BioorthogonalChemistry #ChemicalBiology #Biochemistry #Pharmacology #Oncology #sflorg
https://www.sflorg.com/2026/06/bchm06032601.html
Programmable Chemistry: The TRACE Method

Discover how TRACE programmable chemistry uses tetrazine cages to precisely target diseased cells for safer drug delivery and imaging.

We are very happy that Peng Chen from Peking University visited us today for a very well attended LED3 Lecture. He talked about "Live-cell Protein Chemistry in Health and Disease".

https://www.nature.com/articles/s41557-024-01463-7

#Cells #BioorthogonalChemistry #Chemistry #ChemBio

Great piece by the very talented
Claire O'Connell out on The Irish Times @irishtimes celebrating the #ChemNobel to #ClickChemistry and #BioOrthogonalChemistry with some enthusiastic feedback from me and Andrew Kellet

@bertozzi I hope you'll like it 😊👏👏👏

https://www.irishtimes.com/science/2022/12/01/click-and-collect-the-nobel-prize-in-chemistry/

#glycotime #chemiverse #chemistry #Nobel

Click and collect the Nobel Prize in chemistry

Click and bio-orthogonal chemistry open new worlds

The Irish Times