Researchers have designed a novel family of antiviral molecules—sugar-derived aziridines based on the structure of oseltamivir (Tamiflu)—that effectively bind to and inhibit neuraminidase, a key surface protein required for the spread of the influenza virus.
#Virology #Pharmaceutical #Biochemistry #Chemistry #sflorg
https://www.sflorg.com/2026/03/vi03242601.html
New compounds to inactivate a key protein in the influenza virus

Neuraminidase (NA) is one of the key surface enzymes of the influenza virus

The nascent polypeptide-associated complex (NAC) is a critical molecular control center in eukaryotes that binds to emerging amino acid chains at the ribosome. It initiates the essential first steps of folding these chains into their correct three-dimensional functional structures.
#MolecularBiology #CellBiology #Biochemistry #StructuralBiology #sflorg
https://www.sflorg.com/2026/03/mbio03232601.html
New Findings on the First Steps in Protein Synthesis

International research team under heidelberg supervision examines role of NAC complex in essential process of protein folding

Plastic bottles transformed into Parkinson's drug using bacteria

"Scientists at the University of Edinburgh engineered E. coli bacteria to turn a type of plastic used widely in food and drink packaging—polyethylene terephthalate, or PET—into L-DOPA. The process involves first breaking down PET waste—some 50 million tonnes of which are produced annually—into chemical building blocks of terephthalic acid. Molecules of terephthalic acid are then transformed into L-DOPA by the engineered bacteria through a series of biological reactions."

https://phys.org/news/2026-03-plastic-bottles-parkinson-drug-bacteria.html

#sustainability #goodnews #medicine #biochemistry #science

Plastic bottles transformed into Parkinson's drug using bacteria

A drug to treat Parkinson's disease can be made from waste plastic bottles using a pioneering method, a study shows. The approach harnesses the power of bacteria to transform post-consumer plastic into L-DOPA, a frontline medication for the neurological disorder. It is the first time a natural, biological process has been engineered to turn plastic waste into a therapeutic for a neurological disease, researchers say.

Phys.org
Brain cells utilize microscopic, tube-like structures known as "tunneling nanotubes" to physically transfer toxic mutant huntingtin proteins to neighboring cells, thereby driving the progression of #Huntington's disease.
#Neuroscience #MolecularBiology #CellBiology #Biochemistry #sflorg
https://www.sflorg.com/2026/03/ns03202601.html
Discovery of Tiny Cell ‘Tunnels' Could Slow Huntington’s Disease

Tunneling nanotubes form connections between brain cells that express Rhes, a protein linked to Huntington’s disease

Researchers have developed and observed a light-switchable blood pressure medication that alters its molecular shape and potency when exposed to specific wavelengths of light. This advancement allows the drug's therapeutic effects to be modulated with precise timing and localization within the body.
#Photopharmacology #StructuralBiology #Biochemistry #Pharmacology #sflorg
https://www.sflorg.com/2026/03/phar03192601.html
Blood pressure-lowering drug with a light switch

Rendering a drug effective or ineffective in a flash at the appropriate location – this is the focus of research in photopharmacology

Health effects of zinc (toxicity and biological functions) #zinc #toxicity #heavymetal #biochemistry
... Continue to: https://youtube.com/shorts/tM1S7MDe53E?si=FQuEzrRysIh4Sz2-

Job Alert

Research associate in AI-guided barley adaptation to rising temperatures (m/f/d)  

Deadline: 2026-04-22  
Locations: Germany - Halle

https://www.academiceurope.com/ads/research-associate-in-ai-guided-barley-adaptation-to-rising-temperatures-m-f-d/

#hiring #PlantScience #Proteomics #AIinScience #CropScience #ClimateResearch #Biology #biochemistry

#Biochemistry2026 comes to an end!

We especially want to thank our organizers, Claudia Höbartner and Kathrin Lang, for an amazing job and all participants for making this a great conference.

We wish everyone safe travels back and hope to see many of you at the next event in 2028.

#Biochemistry #Chemistry #ChemBio

CC: @gdch

Congratulations to the three winners of the poster awards at #Biochemistry2026:

Felix Veitl
Stefan Jungwirth
Evgeniia Dorinova

We thank the Royal Society of Chemistry and Wiley for sponsoring the poster prizes!

The poster awards were awarded for the following posters: (1/4)

#Biochemistry #Chemistry #ChemBio #Poster #Awards

In the final talk of #Biochemistry2026, Stefan Raunser gave an exciting overview of his group's research on "Unlocking the secrets of the cytoskeleton and heart muscle".

https://www.annualreviews.org/content/journals/10.1146/annurev-biochem-052521-042909
#Biochemistry #Chemistry #ChemBio #Structure #cryoEM
CC @gdch