Mastodawn

Fermented foods that can be deadly!

The soil-borne bacteria Burkholderia cocovenenans produces bongkrekic acid, a potent respiratory toxin - which can be found in poorly prepared fermented coconut or corn products. Not common where I live, but more so in Indonesia and China, so be cautious about eating tempe bongkrek!

https://www.scientificamerican.com/article/death-by-fermented-food/

#FermentedFoods #FoodPoisoning #BacterialToxin #Corn #Coconut

Death by Fermented Food

Some fermenting foods can carry the risk of a bacterium that produces an extremely strong toxin called bongkrekic acid

Scientific American

PLOS Biology Nov 10, 2023

Wnt signaling uses 10 receptors (FZD1-10) in humans, complicating therapeutic targeting. Study shows that a #BacterialToxin fragment can specifically inhibit #WntSignaling mediated by a subset (FZD1, 2, 7), with potential for #cancer treatment #PLOSBiology https://plos.io/3u1KVFO

Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth

Wnt signaling is transmitted via ten homologous Frizzled receptors (FZD1-10) in humans, complicating the therapeutic use of inhibitors due to side-effects. This study shows that a bacterial toxin fragment can be used as a tool to specifically inhibit Wnt signaling mediated by a subset of Frizzed receptors (FZD1, 2, 7), with potential for cancer treatment.