#Monitoring of #Astroviruses, #Brno - #Hantaviruses, #Coronaviruses, #Influenza Viruses, #Bornaviruses, #Morbilliviruses, #Lyssaviruses and #Pestiviruses in Austrian #Bats https://www.mdpi.com/1999-4915/16/8/1232

Using RT-qPCR, 36 samples revealed + or susp. results for astroviruses, Brno-hantaviruses, & CoVs in 9 bat species. Sequencing revealed correspondent sequences in 5 samples. In contrast, none of tested samples was positive for flu A/C/D, bornaviruses, morbilliviruses, lyssaviruses, or pestiviruses.

Monitoring of Astroviruses, Brno-Hantaviruses, Coronaviruses, Influenza Viruses, Bornaviruses, Morbilliviruses, Lyssaviruses and Pestiviruses in Austrian Bats

Here, we report the results of a monitoring study of bat viruses in Austria to strengthen the knowledge of circulating viruses in Austrian bat populations. In this study, we analyzed 618 oropharyngeal and rectal swab samples from 309 bats and 155 pooled tissue samples from dead bats. Samples were collected from 18 different bat species from multiple locations in Austria, from November 2015 to April 2018, and examined for astroviruses, bornaviruses, coronaviruses, hantaviruses, morbilliviruses, orthomyxoviruses (influenza A/C/D viruses), pestiviruses and rhabdoviruses (lyssaviruses) using molecular techniques and sequencing. Using RT-qPCR, 36 samples revealed positive or suspicious results for astroviruses, Brno-hantaviruses, and coronaviruses in nine different bat species. Further sequencing revealed correspondent sequences in five samples. In contrast, none of the tested samples was positive for influenza viruses A/C/D, bornaviruses, morbilliviruses, lyssaviruses, or pestiviruses.

MDPI
MLB #astroviruses can cause #gastroenteritis & neurological problems in vulnerable individuals. @HashimA44477600 @LullaValeria &co use a reverse genetics system to reveal genetic elements that lead to MLB #virus #attenuation in human neurons #PLOSBiology https://plos.io/3XWhEr2
Attenuation hotspots in neurotropic human astroviruses

The MLB genogroup of astroviruses are associated with gastroenteritis and severe neurological complications in vulnerable individuals. The development of reverse genetics system for MLB astroviruses reveals genetic elements that are dispensable for viral replication in cell culture but lead to attenuation in human neurons.