To capture this local heterogeneity, the authors developed a #multiphoton #FLIM approach with the Na⁺ indicator ING-2 and #astrocyte labeling, enabling quantitative Na⁺ measurements in individual #astrocytes and their processes. This is important because astrocytic Na⁺ is not just a bulk somatic variable. It varies locally across branches and subdomains, where K⁺ uptake and #glutamate-linked Na⁺ influx are regulated.

#Neuroscience #Imaging

🧠🎨 New paper by Meyer et al: #astrocytic #sodium #homeostasis is not uniform. Using multiphoton #FLIM in #mouse #brain slices and #invivo, they show strong #cellular and #subcellular heterogeneity in astrocytic Na⁺ levels.

Processes contain more Na⁺ than somata, Na⁺ varies between #astrocyte branches, and distinct Na⁺/K⁺-ATPase subunit patterns help tune local K⁺ uptake and #glutamate-linked Na⁺ influx.

🌍 https://doi.org/10.1038/s41467-026-73435-z

#Neuroscience #Astrocytes #Neurobiology #NeuralDynamics

This brief highlights a mechanism by which brain-support cells (astrocytes) can be activated to reduce Alzheimer’s-related plaque and preserve cognition in a model system. For mental health professionals, the material offers insight into the cellular processes that underlie neurodegenerative changes and how glial function may influence cognitive resilience, which can inform considerations of patient care, caregiver education, and interdisciplinary collaboration.

Article Title: Boosting one protein helps the brain fight Alzheimer’s

Link to Science Daily Mind-Brain News: https://nolinkpreview.com/www.sciencedaily.com/releases/2026/05/260502013550.htm

#AlzheimersResearch
#Neuroglia
#Astrocytes
#CognitiveHealth
#Neuroscience
#GlialCells
#BrainHealth
#MolecularBiology
#Neuroinflammation
#MentalHealthScience

Researchers Identify Astrocyte Pathway That Regulates Appetite and Fullness

📰 Original title: Scientists discover hidden brain switch that tells you to stop eating

🤖 IA: It's clickbait ⚠️
👥 Usuarios: It's clickbait ⚠️

View full AI summary: https://killbait.com/en/researchers-identify-astrocyte-pathway-that-regulates-appetite-and-fullness/?redirpost=b88926dc-8771-4ddf-b0ae-c55cf0c57846

#neuroscience #appetite #astrocytes #obesity

Researchers Identify Astrocyte Pathway That Regulates Appetite and Fullness

📰 Original title: Scientists discover hidden brain switch that tells you to stop eating

🤖 IA: It's clickbait ⚠️
👥 Usuarios: It's clickbait ⚠️

View full AI summary: https://killbait.com/en/researchers-identify-astrocyte-pathway-that-regulates-appetite-and-fullness/?redirpost=b88926dc-8771-4ddf-b0ae-c55cf0c57846

#neuroscience #appetite #astrocytes #obesity

Astrocytes Play a Key Role in Forming and Regulating Fear Memories

📰 Original title: These overlooked brain cells may control fear and PTSD

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/astrocytes-play-a-key-role-in-forming-and-regulating-fear-memories/?redirpost=94e1a4cc-43fa-47d1-bc78-fac7f73d856a

#neuroscience #astrocytes #fear #ptsd

Astrocytes Play a Key Role in Forming and Regulating Fear Memories

📰 Original title: These overlooked brain cells may control fear and PTSD

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

View full AI summary: https://killbait.com/en/astrocytes-play-a-key-role-in-forming-and-regulating-fear-memories/?redirpost=94e1a4cc-43fa-47d1-bc78-fac7f73d856a

#neuroscience #astrocytes #fear #ptsd

The brief highlights a shift in understanding of fear and memory, illustrating that non-neuronal cells—astrocytes—play active, real-time roles in forming, recalling, and modulating fear responses. This challenges traditional neuron-centric models and underscores the importance of considering glial contributions when interpreting fear-related processes, which may inform a broader, systems-oriented perspective for mental health practice.

Article Title: These overlooked brain cells may control fear and PTSD

Link to Science Daily Mind-Brain News: https://www dot sciencedaily dot com/releases/2026/04/260403224508 dot htm

These overlooked brain cells may control fear and PTSD
https://www dot sciencedaily dot com/releases/2026/04/260403224508 dot htm
Astrocytes, once thought to be mere brain “support cells,” are now revealed to be key players in fear memory. Researchers found they actively help form, recall, and weaken fear responses by interacting with neurons in real time. Changing astrocyte activity directly altered how strong fear memories became. This breakthrough could lead to entirely new treatments for anxiety-related disorders.
via Mind & Brain News -- ScienceDaily https://www dot sciencedaily dot com/news/mind_brain/
April 4, 2026 at 07:47AM

#neuroscience
#fearconditioning
#PTSDresearch
#astrocytes
#mentalhealthscience

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Maladie #Alzheimer :
-> rôle des cellules #astrocytes qui participent à l'impression des souvenirs à long terme dans le #cerveau + peuvent être directement déclenchés par des expériences émotionnelles intenses répétées.

https://mastodon.social/@cobrate/114132196272432613

enjeux politiques de la peur/haine + syndrome de stress post-traumatique #SPT.

-> rôle des cellules neurones qui encodent la #memoire selon des traces physiques : les engrammes.

enjeux scolaire.

#science #psy #emotion #ecole #politique