Saskia ScheltjensApr 20, 2024
Next to his many other writings and interviews, I will always remember Daniel Dennett #RIP for his incomparable 8th edition of The Philosophical Lexicon http://hdl.handle.net/10427/56709 #thankyou #artificialenzyme
PDF | The Philosophical Lexicon, 8th Edition | ID: jw827p68f | Tufts Digital Library

Javier Díaz-NidoMay 12, 2023

In situ continuous Dopa supply by responsive artificial enzyme for the treatment of Parkinson’s disease

#Neuroscience #Brain #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Neurodegeneration #Parkinson #DOPA #FunctionalNucleicAcid #ArtificialEnzyme #Enzyme #Biotechnology #Biomedicine

https://www.nature.com/articles/s41467-023-38323-w

In situ continuous Dopa supply by responsive artificial enzyme for the treatment of Parkinson’s disease - Nature Communications

Oral dihydroxyphenylalanine (Dopa) administration to replenish neuronal dopamine is a treatment for Parkinson’s disease but induces fluctuations in plasma Dopa levels. Here the authors report a nucleic acid-based responsive artificial enzyme (FNA-Fe3O4) for in situ continuous Dopa production.

Nature