♻️ Second-Line Therapy for H. pylori

🚫 Don’t reuse clarithromycin or levofloxacin.

🔹 Choose rescue regimens based on local resistance or susceptibility testing.

✅ Options: 10–14 day Bismuth Quadruple Therapy (BQT) or Levofloxacin-based Quadruple (guided use only).
#GastroAGI #HPylori #AntibioticStewardship

🍃Antibiotic Stewardship in H. pylori

Smart use of antibiotics boosts eradication & curbs resistance.

🔹 Apply the 4 Ds: Diagnosis, Drug, Dose, Duration
🔹 Use local resistance data & molecular testing
🔹 Prefer 14-day regimens & confirm cure
🔹 Avoid broad-spectrum misuse

#GastroAGI #HPylori #AntibioticStewardship

💊 #Antibiotika: Ergebnisse kürzerer Therapien

🔍 Babette Bürger stellt im Dt. Ärzteblatt die Ergebnisse eines ThemenCheck-Berichts des Instituts für Qualität und Wirtschaftlichkeit im Gesundheitswesen dar, der sich mit der Dauer der Antibiotikaeinnahme befasst hat.

🦠 Insbesondere das Prinzip der #AntibioticStewardship mit dem Ziel, das Risiko von #AntibiotikaResistenzen zu minimieren, könnte für eine verkürzte Therapie sprechen. Gleichzeitig bleiben Fragen offen.

https://www.aerzteblatt.de/themen/antibiotika/antibiotika-ergebnisse-kuerzerer-therapien-75cffed7-73fa-4222-93a2-39be7174ce98

Antibiotika: Ergebnisse kürzerer Therapien – Deutsches Ärzteblatt

Deutsches Ärzteblatt

https://www.cidrap.umn.edu/antimicrobial-stewardship/more-40-primary-care-prescriptions-contain-antibiotics-global-study

#AntibioticStewardship

“The pooled prevalence of inappropriate antibiotic prescriptions was 57.6%.

Among the 37 studies that reported on factors associated with .. the only significant association observed was with higher educational levels of patients”

More than 40% of primary care prescriptions contain antibiotics, global study estimates

The systematic review and meta-analysis of studies from 51 countries also found that 57% of antibiotic prescriptions in primary care were inappropriate. 

@zephyrleifrenner The 5 day course of antivirals isn’t enough for most people who are taken with COVID. We already know it can last much longer than that; there’s been studies where people have died 300+ days after an infection and still had live virus in them. The 5 day course just suppresses counts for a bit, and acts as a selective pressure. The next time, the virus might be resistant, like happens with antibiotics. Antivirals should be given until tests come back negative, which could be indefinitely. #CovidIsntOver #AntibioticStewardship #lang_en

Just had a fucking lightbulb about antibiotic-like agent stewardship, the 5 day course of Paxlovid, and the courses of people’s COVID infections.

Y’all aren’t going to like this lightbulb.

#CovidIsntOver #AntibioticStewardship #lang_en

MeMed BV hits 100,000 patient tests! This rapid diagnostic is transforming infection management by accurately telling bacterial from viral infections in just 15 minutes, helping reduce unnecessary antibiotic use. Huge for precision medicine.
#MedTech #AntibioticStewardship #HealthTech

Early antibiotic treatment in patients hospitalized with non-severe #COVID19 didn't improve outcomes — if anything, early #antibiotics were actually linked to *poorer* clinical outcomes.

https://doi.org/10.1001/jamanetworkopen.2025.11499

#AntibioticStewardship #AntimicrobialResistance #medicine #xRisk

Das #EpidBull 8/2025 veröffentlicht zwei Beiträge zum Thema regionale #Antibiotikaresistenz-Surveillance und #AntibioticStewardship (ABS).

Beschrieben werden das Modellprojekt eines klinikübergreifenden regionalen Resistenzobservatorium sowie ein lokale ABS-Netzwerk.

🔗 https://www.rki.de/DE/Aktuelles/Publikationen/Epidemiologisches-Bulletin/2025/08_25.pdf

A Process Evaluation of an #AntibioticStewardship Intervention for Urinary Tract Infections in #NursingHomes

"...The most common reason for deviating from the advice generated by the decision tool was an unclear illness presentation..."

#Geriatrics #UTI #Antibiotics #InfectiousDisease

https://www.jamda.com/article/S1525-8610(23)00820-4/fulltext?dgcid=raven_jbs_aip_email