Mastodawn

🧬 How did changes at the atomic scale reshape viral infectivity?

🔗 Stoichiometric insights into SARS-CoV-2 spike–ACE2 binding across variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.07.034

📚 CSBJ: https://www.csbj.org/

#COVID19 #SARSCoV2 #SpikeProtein #ACE2 #StructuralBiology #MolecularDynamics #Virology #Biophysics #ComputationalBiology

Giuseppe Michieli Nov 1

HKU25 clade #MERS-related #coronaviruses use #ACE2 as a functional #receptor, https://etidiohnew.blogspot.com/2025/11/hku25-clade-mers-related-coronaviruses.html

HKU25 clade #MERS-related #coronaviruses use #ACE2 as a functional #receptor

Giuseppe Michieli Oct 16

#Bat #sarbecovirus WIV1-CoV bears an adaptive #mutation that alters #spike dynamics and enhances #ACE2 binding, https://etidiohnew.blogspot.com/2025/10/bat-sarbecovirus-wiv1-cov-bears.html

#Bat #sarbecovirus WIV1-CoV bears an adaptive #mutation that alters #spike dynamics and enhances #ACE2 binding

Giuseppe Michieli Jul 25, 2025

HKU5 #bat #merbecoviruses engage bat and #mink #ACE2 as entry #receptors, https://etidiohnew.blogspot.com/2025/07/hku5-bat-merbecoviruses-engage-bat-and.html

HKU5 #bat #merbecoviruses engage bat and #mink #ACE2 as entry #receptors

Giuseppe Michieli Jul 22, 2025

#ACE2-like enzymatic activity in #COVID19 #convalescents with persistent pulmonary symptoms associated with #immunoglobulin, https://etidiohnew.blogspot.com/2025/07/ace2-like-enzymatic-activity-in-covid19.html

#ACE2-like enzymatic activity in #COVID19 #convalescents with persistent pulmonary symptoms associated with #immunoglobulin

jedisay Jul 14, 2025

Misskey Hubで、サブマリンさんの「タイムラインを見てみる」で、

タイムラインに流れる活字が他より多いように感じたので、登録させて頂きました。　よろしくお願いします。 #ACE2

Giuseppe Michieli Jun 17, 2025

In vitro and in vivo characterization of a #bat #merbecovirus with #ACE2- and #DPP4-independent cell entry, https://etidiohnew.blogspot.com/2025/06/in-vitro-and-in-vivo-characterization.html

In vitro and in vivo characterization of a #bat #merbecovirus with #ACE2- and #DPP4-independent cell entry

Giuseppe Michieli Apr 30, 2025

A #MERS-CoV-like #mink #coronavirus uses #ACE2 as entry receptor, https://etidiohnew.blogspot.com/2025/04/a-mers-cov-like-mink-coronavirus-uses.html

A #MERS-CoV-like #mink #coronavirus uses #ACE2 as entry receptor

Giuseppe Michieli Apr 16, 2025

#Bat #sarbecovirus WIV1-CoV bears an adaptive #mutation that alters spike dynamics and enhances #ACE2 binding, https://etidiohnew.blogspot.com/2025/04/bat-sarbecovirus-wiv1-cov-bears.html

#Bat #sarbecovirus WIV1-CoV bears an adaptive #mutation that alters spike dynamics and enhances #ACE2 binding

Giuseppe Michieli Feb 20, 2025

#Bat-infecting #merbecovirus HKU5-CoV #lineage 2 can use #human #ACE2 as a cell entry receptor, https://etidiohnew.blogspot.com/2025/02/bat-infecting-merbecovirus-hku5-cov.html