Detection of a #Merbecovirus with potential #ACE2 usage in #France

#Species - and #variant - specific #ACE2 compatibility shapes #SARS-CoV-2 #spillover potential in North American #cervids

๐Ÿงฌ How did changes at the atomic scale reshape viral infectivity?

๐Ÿ”— Stoichiometric insights into SARS-CoV-2 spikeโ€“ACE2 binding across variants. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.07.034

๐Ÿ“š CSBJ: https://www.csbj.org/

#COVID19 #SARSCoV2 #SpikeProtein #ACE2 #StructuralBiology #MolecularDynamics #Virology #Biophysics #ComputationalBiology

HKU25 clade #MERS-related #coronaviruses use #ACE2 as a functional #receptor

#Bat #sarbecovirus WIV1-CoV bears an adaptive #mutation that alters #spike dynamics and enhances #ACE2 binding

HKU5 #bat #merbecoviruses engage bat and #mink #ACE2 as entry #receptors

#ACE2-like enzymatic activity in #COVID19 #convalescents with persistent pulmonary symptoms associated with #immunoglobulin

Misskey Hubใงใ€ใ‚ตใƒ–ใƒžใƒชใƒณใ•ใ‚“ใฎใ€Œใ‚ฟใ‚คใƒ ใƒฉใ‚คใƒณใ‚’่ฆ‹ใฆใฟใ‚‹ใ€ใงใ€

ใ‚ฟใ‚คใƒ ใƒฉใ‚คใƒณใซๆตใ‚Œใ‚‹ๆดปๅญ—ใŒไป–ใ‚ˆใ‚Šๅคšใ„ใ‚ˆใ†ใซๆ„Ÿใ˜ใŸใฎใงใ€็™ป้Œฒใ•ใ›ใฆ้ ‚ใใพใ—ใŸใ€‚ใ€€ใ‚ˆใ‚ใ—ใใŠ้ก˜ใ„ใ—ใพใ™ใ€‚
#ACE2
In vitro and in vivo characterization of a #bat #merbecovirus with #ACE2- and #DPP4-independent cell entry, https://etidiohnew.blogspot.com/2025/06/in-vitro-and-in-vivo-characterization.html
In vitro and in vivo characterization of a #bat #merbecovirus with #ACE2- and #DPP4-independent cell entry

A #MERS-CoV-like #mink #coronavirus uses #ACE2 as entry receptor